Research Groups and Network Resources - PGRN Web Site

Research Groups

The following research groups are members of the PGRN. Click on the acronyms to see project descriptions and participants. Contact the PIs for more details.

NWAP
Pharmacogenetics in Rural and Underserved Populations
PI: Kenneth E. Thummel, Ph.D. and Wylie Burke, M.D. Ph.D.
Project Website
Publications
NWAP File Sharing (NWAP Members only)

PAAR
Pharmacogenomics of Anticancer Agents Research Group
PI: Mark J. Ratain, M.D., Nancy J. Cox, Ph.D., M. Eileen Dolan, Ph.D.
Project Website
Publications

PAAR4Kids
Pharmacogenomics of Anticancer Agents Research in Children
PI: Mary V. Relling, Pharm.D.
Project Website
Publications

PAPI-2
Pharmacogenomics of Anti-Platlet Intervention-2 (PAPI-2) Study
PI: Alan R. Shuldiner, M.D.
Publications

PARC
Pharmacogenomics and Risk of Cardiovascular Disease
PI: Ronald M. Krauss, M.D., Deborah A. Nickerson, Ph.D., Jerome I. Rotter, M.D.
Project Website
Publications

PAT
Pharmacogenomics of Arrhythmia Therapy
PI: Dan M. Roden, M.D.
Project Website
Publications

PEAR
Pharmacogenomic Evaluation of Antihypertensive Responses
PI: Julie A. Johnson, Pharm.D.
Project Website
Publications

PGBD
Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder
PI: John R. Kelsoe, M.D.
Publications

PHAT
Pharmacogenetics of Asthma Treatment
PI: Scott T. Weiss, M.D., M.S. and Kelan G. Tantisira, M.D., M.P.H.
Project Website
Publications

PhRAT
Pharmacogenomics of Rheumatoid Arthritis Therapy
PI: Robert Plenge, M.D., Ph.D.
Publications

PMT
Pharmacogenetics of Membrane Transporters
PI: Kathleen M. Giacomini, Ph.D.
Project Website
Publications

PNAT
Pharmacogenetics of Nicotine Addiction Treatment
PI: Caryn Lerman, Ph.D., Rachel Tyndale, Ph.D.
Publications

PPII
Pharmacogenetics of Phase II Drug Metabolizing Enzymes
PI: Richard M. Weinshilboum, M.D., Liewei Wang, M.D., Ph.D.
Project Website
Publications

XGEN
Expression Genetics in Drug Therapy
PI: Wolfgang Sadee, Dr.rer.nat.
Project Website
Publications

Network Resources

The following network resources are available to the PGRN members. Some are developing limited pilot projects as proof-of-principle, and some are accepting proposals on an ongoing basis. Contact the PIs for details. Any open calls for proposals are found at Instructions and Forms.

PGRN-CGM
Pharmacogenomics Research Network & Center for Genomic Medicine Global Alliance
PI: Kathleen M. Giacomini, Ph.D.
Project Website
Publications

PGRN-RIKEN CGM Collaborative Studies

PGRN-CGM Network Resource Access Guide

P-STAR
PGRN Statistical Analysis Resource
PI: Marylyn D Ritchie, Ph.D.
Project Website
Publications

Workshops Sponsored by P-STAR

P-STAR Network Resource Access Guide

PG-POP
PharmacoGenomic discovery and replication in very large patient POPulations
PI: Dan M. Roden, M.D.
Project Website
Publications

PGRN Projects Funded Through PGPop

PG-POP Network Resource Access Guide

PHONT
PGRN Ontology Network Resource
PI: Christopher G. Chute, M.D., Dr.PH.
Project Website
Publications

PHONT Network Resource Access Guide

PHONT Contact List

DEEP SEQUENCING RESOURCE
Eric Wieben, Ph.D., Coordinator
Publications

PGRN Projects Funded Through the DSR

DSR Network Resource Access Guide

PGRN Partners

The following groups are partners working with the PGRN. Contact the PIs for details.

PharmGKB
Pharmacogenomics Knowledge Base
PI: Russ Altman, M.D., Ph.D.
Project Website
Publications

ELSI
ELSI and Pharmacogenomics
PI: Ellen Clayton, J.D., M.D., M.S.
Publications

LCL
Cell Based Resources for Pharmacogenomic Studies
PI: M. Eileen Dolan, Ph.D.
Publications