James M. Hoffman PharmD, MS is an Associate Member in Pharmaceutical Sciences and the Chief Patient Safety Officer at St. Jude Children’s Research Hospital in Memphis, Tennessee. His career has focused on evaluating and improving complex medication use systems, and he currently provides leadership of patient safety activities across St. Jude. His research focuses on advancing pharmacogenetics as a proactive medication safety strategy, including St. Jude’s implementation effort and nationally through the Clinical Pharmacogenetic Implementation Consortium (CPIC). Through these efforts he works to accelerate implementation of research discoveries in pharmacogenomics into the clinic through the development and dissemination of model practices and clinical practice guidelines. He has experience developing and refining clinical decision support for pharmacogenetics in electronic health records, which informs his leadership of the CPIC Informatics group with colleagues from Mayo Clinic and Stanford.