We recently celebrated 10 years of genome-wide association (GWA) studies, which have lead to a broad range of discoveries and unprecedented opportunities to identify new therapeutic targets (see review). The number of GWA studies of pharmacogenomics is steadily increasing though still behind studies related to human disease and traits.
The NHGRI-EBI GWAS Catalog (ref), is a great resource, cataloging all published GWA studies and enabling users to search for particular gene, variants and studies of interest and their associated p-values, references and other features. The GWAS Catalog also has an extensive list of summary statistics for various published studies. In addition, users can download list of studies and associated variants and p-values, to perform further types of analyses, such as effect size comparison (ref), number and types of studies (ref, ref), number of variants and traits (ref) and others.
For those who are interested with a list of published GWA studies on pharmacogenomics, here is a list of published GWA studies, extracted from GWAS Catalog (updated July 10th 2017) on pharmacogenomics, related to drug response, adverse events and drug levels. Currently there are over 277 publications on pharmacogenomics GWA studies. Should you know of any PGx study missing here, please contact firstname.lastname@example.org. Please visit PGRN tools page to check out other tools.
The Hub team