Dr. Karnes' primary area of research interest is cardiovascular pharmacogenomics, specifically investigating the utility of genetic polymorphisms to predict toxicities of cardiovascular drugs. He employs a translational approach to investigate pharmacogenomic associations using observational studies, functional genomics techniques, and eventually prospective clinical trials. His ultimate career goal is to facilitate personalized cardiovascular medicine and genotype-guided prescribing to avoid serious cardiovascular drug toxicities.
In September 2015, Dr. Karnes joined the faculty at the University of Arizona, College of Pharmacy in the Department of Pharmacy Practice & Science. He is an author on twenty two peer-reviewed manuscripts and twenty six abstracts presented at national and international meetings. He is active in multiple professional societies including the American Society for Clinical Pharmacology and Therapeutics, the American Heart Association, and the American College of Clinical Pharmacy. He is supported by an American Heart Association Scientist Development Grant and an American College of Clinical Pharmacy Research Institute’s Futures Award.