NIGMS Launches a New Research Network Focused on Precision Medicine

The National Institute of General Medical Sciences has sponsored the Pharmacogenomics Research Network, PGRN, since 2015. In July, NIGMS renewed the PGRN with a focus on precision medicine.  The new awards include three research centers, two enabling resources, a knowledge base, PharmGKB, and hub, PGRN-Hub, which serves to catalyze scientific collaborations in precision medicine.

​The three PGRN centers are listed below alphabetically by principal investigator: 
Center for Pharmacogenomics of Statin Therapy
Ronald Krauss, MD, Children’s Hospital Oakland Research Institute (Calif.)
Aldons Jake Lusis, PhD, University of California, Los Angeles

Center for Precision Medicine in Leukemia
Mary V. Relling, PharmD, St. Jude Children’s Research Hospital, Memphis, Tenn.
Mignon Loh, MD, University of California Benioff Children's Hospital

Center for Improving Prediction of Drug Action
Dan M. Roden, Vanderbilt University School of Medicine, Nashville, Tenn.
Elizabeth J. Phillips, MD, Vanderbilt University School of Medicine, Nashville, Tenn.
Joshua C. Denny, MD, MS, Vanderbilt University School of Medicine, Nashville, Tenn.


PGRN enabling resources are listed below alphabetically by principal investigator:

PharmGKB: Pharmacogenomics Knowledge for Precision Medicine
Russ Altman, MD, PhD, Stanford University
Teri Klein, PhD, Stanford University

PGRN Hub
Kathy Giacomini, PhD, University of California San Francisco
Graham Johnson, PhD, University of California San Francisco

F-CAP: Functionalization of Variants in Clinically Actionable Pharmacogenes
Doug Fowler, University of Washington 
Allan Rettie, University of Washington
  
Clinical Pharmacogenetics Implementation Consortium (CPIC)
Mary V. Relling, PharmD, St. Jude Children’s Research Hospital, Memphis, Tenn.
Teri Klein, PhD, Stanford University