NHGRI, released two funding opportunities relevant to laboratory and clinical research to translate genomic and genetic research into understanding and treating human diseases.
Investigator-Initiated Genomic Medicine Research
PAR-18-735 & PAR-18-736
This supports research opportunities designed to advance the understanding and implementation of genomic information about an individual to inform clinical care, and the health outcomes of that clinical use.
Novel Approaches for Relating Genetic Variation to Function & Disease
PA-18-867 & PA-18-868
Genome-wide association studies have found many variants that are statistically associated with disease and other traits. In addition, clinical genomic sequencing studies have identified many variants in healthy and diseased individuals, where the pathogenicity of such variants is often unknown, leading to their classification as variants of uncertain significance (VUS). This program aims to support the development of novel and generalizable approaches to study how genetic variants lead to differences in function and to study how such functional differences affect human health and disease processes, or how this knowledge can be used clinically.
The Hub team