Pharmacogenomics Research Network

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What is PGRN?
About PGRN

Our Objective

The mission of the Pharmacogenomics Research Network (PGRN) is to catalyze and lead research in precision medicine for the discovery and translation of genomic variation influencing therapeutic and adverse drug effects.

Who We Are

A new PGRN, PGRN IV, established July 1, 2015, represents a continuation of these research activities, however in a new model. This new model invites participation of all investigators with an interest in pharmacogenomics research to be part of the new network.

Currently, the newly formed PGRN consists of three large center grant projects, two enabling resources for pharmacogenomics, a knowledgebase, PharmGKB, and a PGRN Hub, established to coordinate activities of the new PGRN in order to catalyze research in pharmacogenomics and precision medicine.

Member Benefits

Reduced registration fees for PGRN meetings and workshops, including member receptions and poster sessions at annual ASHG (and ASCPT) meeting.
Participation in member-wide quarterly calls/webinars and monthly Research in Progress Seminars
Membership on PGRN program committees for meetings and workshops
Network with colleagues and establish collaborations
Leadership opportunities for members (e.g., serve on PGRN committees, board, and as leaders)
Awards for trainees
Access to PGRN web pages highlighting pharmacogenomics tools and resources, events and other useful information for PGx research, education and clinical practice
Mentorship opportunities

Resources

Pharmacogenomics Knowledgebase (PharmGKB)

The PharmGKB is a resource that encompasses clinical information including dosing guidelines and drug labels, potentially clinically actionable gene-drug associations and genotype-phenotype relationships.

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Clinical Pharmacogenomics Implementation (CPIC)

CPIC’s goal is to address some of the barriers to implementation of pharmacogenetic tests into clinical practice.

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Pharmacogene Variation Consortium

PharmVar serves as a central repository for pharmacogene variation to facilitate allele (haplotype) designation and the interpretation of pharmacogenetic test results to guide precision medicine.

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Our History

The Pharmacogenomics Research Network, PGRN I–III was funded from 2000 through 2015 by multiple Institutes and Centers of the NIH. The network catalyzed pharmacogenomics discoveries both nationally and internationally through the conduct of collaborative research focused on the discovery and translation of the genetic determinants of drug response, in order to enable safer and more effective drug therapies.

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Become a Member

Membership dues are vital to continue the mission and work of the PGRN. Founding Members will be listed on the PGRN website.