Applying Implementation Science Principles to Enhance the Adoption of Pharmacogenomics

Morning Session

This half-day pre-conference workshop will provide foundational knowledge about how to incorporate implementation science principles into pharmacogenomics implementation.

Faculty from Northwestern University, Feinberg School of Medicine, Department of Medical Social Science and the PGRN IWG will review: 1) Implementation science theories, models, and frameworks; 2) Implementation outcomes, assessments, and study designs; and 4) Implementation strategies.

Application of IS principles will be exemplified through Northwestern’s genomic learning health system. Attendees are encouraged to bring a concept for a specific project they are interested in implementing as the workshop will include activity time to develop their work using implementation science principles.

All of Us Workshop

Afternoon Session (Concurrent)

An interactive, two-part experience designed to accelerate discovery in pharmacogenomics using one of the most diverse biomedical datasets available. This workshop will combine strategic insights with hands-on training to help researchers translate large-scale genomic and EHR data into meaningful clinical applications.

What’s New in 2026: Transition to Workbench 2.0, the CDR v9 data release, expanded short- and long-read sequence data, and integrated Stargazer and HLA allele calling.

Part 1: Advancing PGx Using All of Us will highlight new data, program updates, and innovative research approaches with lighting talks, featuring emerging use cases enabled by new capabilities.

Part 2: Hands-On Workbench Training will provide guided experience using the new Workbench 2.0 and CDR v9 data, equipping participants with practical skills for data access, analysis, and reproducible research workflows.

PGx 201

Afternoon Session (Concurrent)

PGx 201 Preconference builds on the foundational concepts introduced in 2025 PGRN/ClinPGx annual meeting pre-workshop, focusing on practical laboratory implementation and EHR integration required for sustainable pharmacogenomics programs.

The workshop examines key decisions across the PGx testing lifecycle and how laboratory, regulatory, and reporting choices directly affect clinical workflows and patient care.

Participants then explore how PGx results are integrated into the EHR through clinical decision support, knowledge management, and informatics governance, using real-world examples and CPIC resources.

Interactive discussions highlight common implementation challenges, strategies for managing evolving PGx evidence, and emerging technologies such as AI that are shaping the future of clinical pharmacogenomics.