1) Collaborative Cancer PGx Research (CPR), Lead: Britt Drogemoller, Leadership Team: Eileen Dolan, Deana Kroetz, Dan Hertz, Gabriele Stocco, and David Twesigomwe

The purpose of CPR subcommittee is to facilitate opportunities to i) enhance collaborative research among members of the PGRN Oncology SIG and ii) generate high impact research outputs (e.g. publications, grants) for members of this group.

Our 1-year goals are to:

1. Create a repository of previously published data (e.g. GWAS summary statistics)
2. Create a searchable database of PGx oncology cohorts that are available through the SIG to facilitate collaboration between researchers focusing on similar PGx traits, which will results in successful PGRN grant(s)
3. Explore opportunities to integrate PGx research into already existing cancer genetics projects (e.g. CONFLUENCE project)

Our 5-year goals are to:

1. Publish articles from research performed using data housed in the repository
2. Generate collaborative research outputs that are enabled through the use of the searchable database. This includes submission of grants to major funding agencies (e.g. NIH), which include pilot data generated using funds from successful PGRN grant(s).
3. Demonstrate how PGx can be integrated into large-scale cancer projects and identify additional large-scale resources where PGx can be integrated

2) Clinical PGx Implementation (CPI, Lead: Cyrine Haidar) Leadership Team: Cyrine Haidar, April Schultz, Amy Pasternak, Ben Kong, Max Smith, and Chakradhara Uppugunduri

The purpose of the Clinical PGx Implementation subcommittee is to i) serve as hub to connect oncology PGx practitioners and ii) to allow oncology PGx practitioners to seek and exchange implementation successes and challenges,

Our 1-year goals are to:

1. Introduce the PGRN Onc SIG to the oncology implementers in the pharmacogenomics community
2. Understand the current state of clinical gene/drug pair implementations at oncology sites
3. Create a searchable database of pharmacogenomics practitioners to facilitate the discussion and exchange of oncology PGx implementation experience

Our 5-year goals are to:

1. Publish articles highlighting unique implementation aspects at oncology PGx sites
2. Establish a network of oncology pharmacogenomics practitioners
3. Serve as the main forum for PGx oncology practitioners for implementation data sharing and collaboration (for example, with IGNITE)