PGRN Oncology Special Interest Group

The new PGRN Oncology SIG has identified the following three areas of interest. Each area has a subcommittee (~5 individuals) who will help coordinate the activities within that domain. Below are brief descriptions and 1- and 5-year plans for each subcommittee:

R. Stephanie Huang, PhD
University of Minnesota, USA
Group Lead

1) Collaborative Cancer PGx Research (CPR), Lead: Britt Drogemoller, Leadership Team: Eileen Dolan, Deana Kroetz, Dan Hertz, Gabriele Stocco, and David Twesigomwe

The purpose of CPR subcommittee is to facilitate opportunities to i) enhance collaborative research among members of the PGRN Oncology SIG and ii) generate high impact research outputs (e.g. publications, grants) for members of this group.

Our 1-year goals are to:

  1. Create a repository of previously published data (e.g. GWAS summary statistics)
  2. Create a searchable database of PGx oncology cohorts that are available through the SIG to facilitate collaboration between researchers focusing on similar PGx traits, which will results in successful PGRN grant(s)
  3. Explore opportunities to integrate PGx research into already existing cancer genetics projects (e.g. CONFLUENCE project)

Our 5-year goals are to:

  1. Publish articles from research performed using data housed in the repository
  2. Generate collaborative research outputs that are enabled through the use of the searchable database. This includes submission of grants to major funding agencies (e.g. NIH), which include pilot data generated using funds from successful PGRN grant(s).
  3. Demonstrate how PGx can be integrated into large-scale cancer projects and identify additional large-scale resources where PGx can be integrated

Britt Drögemöller, PhD

Assistant Professor and Canada Research Chair in Pharmacogenomics and Precision Medicine

University of Manitoba, Manitoba, Canada

Eileen Dolan, PhD
Professor and Deputy Director of the University of Chicago Medicine Comprehensive Cancer Center
University of Chicago, Chicago, US

Deanna Kroetz, PhD
Professor and Dean of the College of Pharmacy
Ohio State University, Ohio, US

Dan Hertz
Assistant Professor
University of Michigan, Michigan, US

Gabriele Stocco, PhD

Associate Professor and Clinical Pharmacology Manager of Advanced Diagnostics Laboratory

University of Trieste, Trieste, Italy

David Twesigomwe, PhD
Sydney Brenner Charitable Trust Postdoctoral Fellow,
University of the Witwatersrand, Johannesburg, South Africa

2) Clinical PGx Implementation (CPI, Lead: Cyrine Haidar) Leadership Team: Cyrine Haidar, April Schultz, Amy Pasternak, Ben Kong, Max Smith, and Chakradhara Uppugunduri

The purpose of the Clinical PGx Implementation subcommittee is to i) serve as hub to connect oncology PGx practitioners and ii) to allow oncology PGx practitioners to seek and exchange implementation successes and challenges,

Our 1-year goals are to:

  1. Introduce the PGRN Onc SIG to the oncology implementers in the pharmacogenomics community
  2. Understand the current state of clinical gene/drug pair implementations at oncology sites
  3. Create a searchable database of pharmacogenomics practitioners to facilitate the discussion and exchange of oncology PGx implementation experience

Our 5-year goals are to:

  1. Publish articles highlighting unique implementation aspects at oncology PGx sites
  2. Establish a network of oncology pharmacogenomics practitioners
  3. Serve as the main forum for PGx oncology practitioners for implementation data sharing and collaboration (for example, with IGNITE)

Cyrine-Eliana Haidar, PharmD, BCPS, BCOP, FASHP
St. Jude Children's Research Hospital, USA
Lead, Clinical PGx Implementation

PGRN Oncology Research Collaboration Database

PGRN Oncology Research Collaboration Database We have created the PGRN Oncology Research Collaboration Database to provide researchers with information on cohorts that are available through the cancer pharmacogenomics community. Our vision is that this resource will be used to foster global collaborations, enabling the replication of findings and the launch of large-scale collaborative projects.

View PGRN Oncology Research Collaboration Database

If you are interested in joining the PGRN Oncology SIG, please email PGRN Office at

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